姓名：赵洪芝
职务职称：副教授（硕士生导师）
研究领域：环境与健康（污染物的人体暴露、代谢组学等）
邮箱：hongzhizhao@nankai.edu.cn
教育背景
2009.9-2012.12 南开大学药学院化学生物学专业攻读博士学位
2003.9-2006.3 天津大学化工学院生物化工专业攻读硕士学位
1999.9-2003.7 天津大学化工学院制药工程专业攻读学士学位
科研教学经历
2019.9-至今 南开大学环境科学与工程学院，副教授
2014.7-2019.8 香港浸会大学（HKBU）环境与生物分析国家重点实验室，博士后
2013.3-2014.3 比利时鲁汶大学（K. U. Leuven）生物系，博士后
主讲课程：
《环境代谢组学》，研究生课程
《环境健康综合实验》，本科生课程
学术与社会任职
Bulletin of Environmental Contamination and Toxicology 编委
科研项目
1. 国家自然科学基金-面上项目，基于代谢组学的邻苯二甲酸酯暴露及其与年龄交互作用导致妊娠糖尿病机制研究（NSFC 42177412），2022年1月-2025年12月，主持；
2.国家重点研发计划项目“场地土壤污染物环境基准制定方法体系及关键技术”，课题2“本土化场地土壤环境暴露参数方法学与指标体系”（2019YFC1804602），课题骨干；
3. 青年教师研究启动项目，“对羟基苯甲酸酯人体暴露与健康效应”，主持；
4.青年教师研究启动项目，“环境内分泌干扰物的人体暴露及其对健康的影响”，主持；
5.青年教师研究启动项目，“多环芳烃的人体暴露研究”，主持；
6. 国家自然科学基金-青年基金：基于质谱技术的双酚A与DNA加合物检测方法的研究及其应用（NSFC 21505111），2016年1月-2018年12月，主持；
7. 国家自然科学基金-重点项目：太原和广州市大气细颗粒物诱导呼吸系统疾病的质谱代谢组学研究（NSFC 91543202），2016年1月-2019年12月，参与。
学术论著
发表SCI论文78篇，总引用1800余次，谷歌H指数24，其中以第一作者或通讯作者共发表SCI收录文章共24篇，部分代表作如下：
（1） 一作或通讯作者文章：
1. Yuanyuan Zheng, Mian Bao, Yiming Yao, Maosen Zhao, Hao Chen, Hongwen Sun, Cuirong Sun, Hongzhi Zhao*, Yuanjiang Pan*, Discovery of 35 novel classes of per- and polyfluoroalkyl substances in representative commercial fluorinated products in China, Journal of Hazardous Materials, 2023, 457, 131780
2. Sai Guo, Liting Hua, Wu Liu, Hongxiu Liu, Qiusheng Chen, Yongcheng Li, Xiaoxiao Li, Leicheng Zhao, Ruoqi Li, Zining Zhang, Chong Zhang, Lin Zhu, Hongwen Sun, Hongzhi Zhao*, Multiple metal exposure and metabolic syndrome in elderly individuals: A case-control study in an active mining district, Northwest China, Chemosphere, 2023, 326,138494
3. Zining Zhang, Sai Guo, Liting Hua, Beibei Wang, Qiusheng Chen, Lu Liu, Li Xiang, Hongwen Sun, Hongzhi Zhao*, Urinary levels of 14 metal elements in general population: A region-based exploratory study in China, Toxics, 2023, 11(6): 488
4. Liting Hua#, Wu Liu#, Yarui Liu, Ming Yang, Beibei Wang, Hongkai Zhu, Lin Zhu, Yiming Yao, Yuqin Zhang, Hongzhi Zhao*, Occurrence and profile characteristics of environmental phenols in human urine from a rural area in Northwestern China, Environmental Pollution, 2022, 315,120405
5. Liting Hua, Sai Guo, Jiaping Xu, Xiaomeng Yang, Hongkai Zhu, Yiming Yao, Lin Zhu, Yongcheng Li, Jingran Zhang, Hongwen Sun, Hongzhi Zhao*,Phthalates in dormitory dust and human urine: A study of exposure characteristics and risk assessments of university students,Science of the Total Environment, 2022, 845: 157251
6. Hongzhi Zhao, Yuanyuan Zheng, Lin Zhu, Li Xiang, Shunqing Xu*, Zongwei Cai*, Trimester-specific urinary metabolome alterations associated with gestational diabetes mellitus: A study in different pregnancy stages, Chinese Chemical Letters, 2022, 33(6), 3139-3143
7. Liting Hua, Sai Guo, Yu Wang, Hongwen Sun*, Hongzhi Zhao*, Simultaneous determination of multiple isomeric hydroxylated polycyclic aromatic hydrocarbons in urine by using ultra-high performance liquid chromatography tandem mass spectrometry, Journal of Chromatography B, 2021,1184: 122983
8. Xiaoxiao Wang, Guodong Cao, Zhiyi Yang, Hongzhi Zhao*, Zongwei Cai*, DNA and RNA adducts formation from 3,4-quinone metabolites of bisphenol F, Environmental Science & Technology Letters, 2021, 8(11), 1009-1014
9. Yuanyuan Zheng#, Hongzhi Zhao#, Man Tong, Lin Zhu, Stephanie Ma*, Zongwei Cai*, Characterization and determination of 13C-labeled non-essential amino acids in 13C5-glutamine isotope tracer experiment with a mass spectrometry strategy combining parallel reaction monitoring and multiple reaction monitoring, Analytical Chemistry, 2021, 93(40): 13564-13571 (co-first author)
10. Hongzhi Zhao#, Yuanyuan Zheng#, Lin Zhu, Li Xiang, Yanqiu Zhou, Jiufeng Li, Jing Fang, Shunqing Xu, Wei Xia*, Zongwei Cai*, Paraben exposure related to purine metabolism and other pathways revealed by mass spectrometry-based metabolomics,Environmental Science & Technology, 2020, 54(6): 3447-3454
11. Hongzhi Zhao#, Han Li#, Yuanyuan Zheng, Lin Zhu, Jing Fang, Li Xiang, Shunqing Xu, Yanqiu Zhou, Hemi Luan, Wei Xia*, Zongwei Cai*, Association of altered serum acylcarnitine levels in early pregnancy and risk of gestational diabetes mellitus, SCIENCE CHINA Chemistry, 2020, 63(1): 126-134
12. Jie Hu#, Hongzhi Zhao#,Joseph M, Braun, Tongzhang Zheng, Bin Zhang, Wei Xia, Wenxin Zhang, Jiufeng Li, Yanqiu Zhou, Han Li, Jun Li, Aifen Zhou, Yiming Zhang, Stephen L, Buka, Simin Liu, Yang Peng, Chuansha Wu, Minmin Jiang, Wenqian Huo, Yingshuang Zhu, Kunchong Shi, Yuanyuan Li, Zongwei Cai*, Shunqing Xu*, Associations of trimester-specific exposure to bisphenols with size at birth: A Chinese prenatal cohort study, Environmental Health Perspectives, 2019, 127(10): 107001 (co-first author)
13. Yangqian Jiang#, Hongzhi Zhao#,Wei Xia, Yuanyuan Li, Hongxiu Liu, Ke Hao, Jia Chen, Xiaojie Sun, Wenyu Liu, Jiufeng Li, Yang Peng, Chen Hu, Chunhui Li, Bin Zhang, Shi Lu, Zongwei Cai*, Shunqing Xu*, Prenatal exposure to benzophenones, parabens and triclosan and neurocognitive development at 2 years, Environment International, 2019, 126: 413-421 (co-first author)
14. Hongzhi Zhao#, Han Li#, Arthur Chi Kong Chung, Li Xiang, Xiaona Li, Yuanyuan Zheng, Hemi Luan, Lin Zhu, Wenyu Liu, Yang Peng, Yaxing Zhao, Shunqing Xu, Yuanyuan Li*, Zongwei Cai*, Large-scale longitudinal metabolomics study reveals different trimester-specific alterations of metabolites in relation to gestational diabetes mellitus, Journal of Proteome Research, 2019, 18 (1): 292-300
15. Yuanyuan Zheng#, Hongzhi Zhao#, Lin Zhu, Zongwei Cai*, Comprehensive identification of steroid hormones in human urine based on liquid chromatography-high resolution mass spectrometry, Analytica Chimica Acta, 2019, 1089:100-107 (co-first author)
16. Hongzhi Zhao, Jiufeng Li, Yanqiu Zhou, Lin Zhu, Yuanyuan Zheng, Wei Xia, Yuanyuan Li, Li Xiang, Wei Chen, Shunqing Xu*, Zongwei Cai*, Investigation on metabolism of di(2-ethylhexyl) phthalate in different trimesters of pregnant women, Environmental Science & Technology, 2018, 52(21): 12851-12858
17. Hongzhi Zhao, Juntong Wei, Li Xiang, Zongwei Cai*, Mass spectrometry investigation of DNA adduct formation from bisphenol A quinone metabolite and MCF-7 cell DNA, Talanta, 2018,182(5): 583-589
18. Hongzhi Zhao, Jiufeng Li, Xinli Ma, Wenqian Huo, Shunqing Xu*, Zongwei Cai*, Simultaneous determination of bisphenols, benzophenones and parabens in human urine by using UHPLC-TQMS, Chinese Chemical Letters, 2018, 29:102-106
19. Hongzhi Zhao#, Wenqian Huo#, Jiufeng Li, Xinli Ma, Wei Xia, Zhengji Pang, Mingyi Xie, Shunqing Xu*, Zongwei Cai*,Exposure to benzophenones, parabens and triclosan among pregnant women in different trimesters, Science of the Total Environment, 2017, 607-608:578-585
（2）其他共同作者文章：
1. Man Tong*, Tin-LokWong, Hongzhi Zhao, Yuanyuan Zheng, Yu-Nong Xie, Cheuk-Hin Li, Lei Zhou, Noélia Che, Jing-Ping Yun, Kwan Man, Terence Kin-Wah Lee, Zongwei Cai*, StephanieMa*, Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer, Cell Reports, 2021, 36 (8): 109617
2. Hemi Luan, Hongzhi Zhao, Jiufeng Li, Yanqiu Zhou, Jing Fang, Hongxiu Liu, Yuanyuan Li, Wei Xia, Shunqing Xu*, Zongwei Cai*, Machine learning for investigation on endocrine-disrupting chemicals with gestational age and delivery time in a longitudinal cohort, Research, 2021, 9873135
3. Jing Fang, Hongzhi Zhao, Yanhao Zhang, Minghua Lu, Zongwei Cai*, Atmospheric pressure chemical ionization in gas chromatography-mass spectrometry for the analysis of persistent organic pollutants, Trends in Environmental Analytical Chemistry, 2020, 25: e00076.
4. Jing Fang, Hongzhi Zhao, Yanhao Zhang, Minghung Wong, Yu He, Qianqian Sun, Shunqing Xu*, Zongwei Cai*, Evaluation of gas chromatography-atmospheric pressure chemical ionization tandem mass spectrometry as an alternative to gas chromatography tandem mass spectrometry for the determination of polychlorinated biphenyls and polybrominated diphenyl ethers, Chemosphere, 2019, 225: 288-294
5. Jing Fang, Hongzhi Zhao, Yanhao Zhang, Yu He, Qianqian Sun, Shunqing Xu*, Zongwei Cai*, Performance of atmospheric pressure gas chromatography-tandem mass spectrometry for the analysis of organochlorine pesticides in human serum, Analytical and Bioanalytical Chemistry, 2019, 411:4185-4191
6. Jiufeng Li, Hongzhi Zhao, Yanqiu Zhou, Shunqing Xu*, Zongwei Cai*, Nine phthalate metabolites in human urine for the comparison of health risk between population groups with different water consumptions, Science of The Total Environment, 2019, 649: 1532-1540
7. Qian Wu, Hongzhi Zhao, Xiangfeng Chen, Zongwei Cai*, Interaction of Bisphenol A 3, 4-quinone Metabolite with Human Hemoglobin, Human Serum Albumin and Cytochrome c in vitro, Chemosphere, 2019, 220: 930-936
8. Hongna zhang, Xiaojian Shao, Hongzhi Zhao,Xiaona Li, Juntong Wei, Chunxue Yang, Zongwei Cai*, Integration of Metabolomics and Lipidomics Reveals Metabolic Mechanisms of Triclosan-Induced Toxicity in Human Hepatocytes, Environmental Science & Technology, 2019, 53, 5406-5415
9. Jiufeng Li#, Chuansha Wu#, Hongzhi Zhao, Yanqiu Zhou, Guodong Cao, Zhiyi Yang, Yanjun Hong, Shunqing Xu, Wei Xia*, Zongwei Cai*, Exposure assessment of bisphenols in Chinese women during pregnancy: a longitudinal study, Environmental Science & Technology, 2019, 53, 13, 7812-7820
10. Jiufeng Li#, Wenyu Liu#, Wei Xia, Hongzhi Zhao, Yanqiu Zhou, Yuanyuan Li, Chuansha Wu, Hongxiu Liu, Bin Zhang, Yingshuang Zhu, Jie Hu, Xianliang Wang, Dan Ye, Shunqing Xu*, Zongwei Cai*, Variations, determinants, and co-exposure patterns of personal care product chemicals among Chinese pregnant women: a longitudinal study, Environmental Science & Technology, 2019, 53, 11, 6546-6555
荣誉与奖励
协助指导硕士生获得南开大学优秀硕士学位论文，“典型环境内分泌干扰物的人体暴露评估研究”，2022年
指导本科生获得环境科学与工程学院优秀毕业论文，“重金属暴露与血压的关联性研究”，2022年
