钟文珏

1.       京津冀环境综合治理国家科技重大专项子课题，京津冀区域本土物种生物毒性测试及其毒理探索，2025.09-2028.08

2.       国家自然科学基金(面上基金) 《全氟壬烯氧基苯磺酸钠(OBS)对小鼠的慢性肾毒性及分子机制》2025.01-2028.12

3.       国家重点研发计划课题《场地未定标特征污染物的多介质分配迁移规律研究》2022.10-2026.09 主持，在研

4.       天津市自然科学基金重点项目《场地典型未定标污染物暴露及风险评估》2023.10-2026.09 主持，在研

5.       国家自然科学基金(面上基金) 《新型低聚类有机磷阻燃剂在斑马鱼体内的富集行为及毒性效应研究》2021.01-2024.12  主持，结题

6.       国家自然科学基金(青年基金) 《新型有机磷阻燃剂RDP及其副产物TPHP在水环境中的分布及水-沉积物界面行为》2017.01-2019.12  主持，结题

7.       天津市自然科学基金《天津水产环境中抗生素和雌激素的分布及迁移转化行为》 2016.04-2019.03  主持，结题

8.       农业部公益项目《天津及河北部分地区水产环境中污染物调查与典型污染物迁移转化行为研究》 2015.1-2019.12  主持，结题

9.       博士点基金《全氟化合物支链/直链异构体在淡水生态系统中的生物富集及沿食物链的生物放大行为研究》 2014.1-2016.12  主持，结题

10.   博士后基金《沉积物中六溴环十二烷对底栖无脊椎动物的毒性效应及作用机制研究——以河蚬为例》 2011-2012  主持，结题

11.    青年教师及海外留学归国人员研究启动项目《PFOS/PFOA及其前体物质在土壤生物体内的富集、转化、迁移规律及异构体选择性研究》  主持，结题

[1]     Yun Deng, Shujun Yi, Yu Zheng, Rouyi Wang, Fang Liu, Wenjue Zhong*, Lingyan Zhu*. Gestational Exposure to Tri-n-butyl Phosphate Induces Maternal Insulin Resistance and Glucose Intolerance by Antagonizing Estrogen Receptor Alpha. Environmental Science & Technology, 2026, 60(12): 8983-8996

[2]     Yang Lyu, Ruyu Guo, Wenjue Zhong*, Lingyan Zhu*. Renal Dysfunction Induced by Sodium p-Perfluorous Nonenoxybenzenesulfonate in Mice: Insights from the Intrinsic Mechanisms of Proteinuria. Environmental Science & Technology, 2025, 59 (22), 10799-10811.

[3]     Yang Lyu, Tianxu Zhang, Wenjue Zhong*, Shujun Yi, Lingyan Zhu*. Exposure to Sodium p-Perfluorous Nonenoxybenzenesulfonate Induces Renal Fibrosis in Mice by Disrupting Lysine Metabolism. Environmental Science & Technology, 2025, 59 (15), 7461-7473.

[4]     Rongyan Yang, Hanfei Bian, Zhou Zhou, Yi Yang, Xiao Wang, Jingshu Xu, Wenjue Zhong*, Lingyan Zhu. Underlying mechanisms of metabolic dysfunction-associated steatotic liver disease induced by 2-ethylhexyl diphenyl phosphate and its hydroxylated metabolite in zebrafish (Danio rerio). Journal of Hazardous Materials, 2025, 493: 138407

[5]     Yang Lyu, Xiao Wang, Yan Wang, Rongyan Yang, Ruyu Guo, Wenjue Zhong*, Lingyan Zhu. Bisphenol A bis(diphenyl phosphate) Disrupts the Homeostasis of Gut Microbiota: A Mechanistic Link to Intestinal Toxicity. Environmental Pollution, 2025, 386: 127221

[6]     Yang Lyu, Yongxiu Ye, Chi Zhang, Wenjue Zhong*, Lingyan Zhu*. Bisphenol A bis (diphenyl phosphate) disrupts tryptophan metabolism through microbiota dysbiosis to promote intestinal toxicity. Environmental Research, 2026, 297,124140

[7]     Yun Deng, Shujun Yi, Chi Zhang, Rongyan Yang, Wenjue Zhong*, Lingyan Zhu*. A meta-analysis based on epidemiological studies to identify the key environmental pollutants inducing gestational diabetes mellitus. Journal of Environmental Science,2025, https://doi.org/10.1016/j.jes.2025.09.041

[8]     Yao Li, Xuhui Zhang, Lingling Xu, Limei Chen, Yukang Wu, Xinliang Ding*, Pengfei Zhu, Wenjue Zhong*. Levels and transport behavior of ionic per- and polyfluoroalkyl substances in the atmosphere of urban pollution scenario: An in-situ investigation of a wastewater treatment plant in Wuxi, China. Environmental Pollution, 2025, 372,126003

[9]     Tianxu Zhang, Yang Lyu, Meng Yuan, Menglin Liu, Yumin Zhu, Binin Sun, Wenjue Zhog*, Lingyan Zhu*, Transformation of 6:6 PFPiA in the gut of Xenopus Laevis: Synergistic Effects of CYP450 Enzymes and Gut Microflora, Journal of Hazardous Materials, 2024, 472: 134535

[10]  Yumin Zhu, Xiaoyu Pan, Yibo jia, Xin Yang, Xiaohua Song, Jiaqi Ding, Wenjue Zhong, Jianfeng Feng, Lingyan Zhu*, Exploring Route-Specific Pharmacokinetics of PFAS in Mice by Coupling in Vivo Tests and Physiologically Based Toxicokinetic Models, Environmental Health Perspectives, 2023, 131(12): 127012

[11]  Rongyan Yang, Yuan Zhang, Yun Deng, Yi Yang, Wenjue Zhong*, Zhu Lingyan*. 2-Ethylhexyl Diphenyl Phosphate Causes Obesity in Zebrafish by Stimulating Overeating via Inhibition of Dopamine Receptor D2. Environmental Science & Technology, 2023, 57(38): 14162–14172

[12]  Tianxu Zhang#, Lingyan Zhu#, Yumeng Sun, Liping Yang, Shujun Yi, and Wenjue Zhong*. Novel Insights on 6:6 Perfluoroalkyl Phosphonic Acid-Induced Melanin Synthesis Disorders Leading to Pigmentation in Tadpoles. Environmental Science & Technology, 2023, 57(30): 11032–11042

[13]  Sihan Wu , Lingyan Zhu , Qingqing Ye , Yumin Zhu , Tianxu Zhang , Xin Chen , Wenjue Zhong*. Mechanisms for the structural dependent transformation of 6:2 and 8:2 polyfluoroalkyl phosphate diesters in wheat (Triticum aestivum L.). Journal of Hazardous Materials, 2023, 454: 131536.

[14]  Rongyan Yang , Yi Yang , Liping Yang , Hao Chen , Wenjue Zhong*, Lingyan Zhu. First insight into the sex-dependent accumulation, tissue distribution and potential toxicities of 2-ethylhexyl diphenyl phosphate and its metabolites in adult zebrafish. Journal of Hazardous Materials, 2023, 452: 131299.

[15]  Yumin Zhu, Yuqing Li, Xiaosong Liu, Xin Yang, Xiaohua Song, Yibo Jia, Wenjue Zhong, Lingyan Zhu*. Bioaccessibility of per- and polyfluoroalkyl substances in food and dust: Implication for more accurate risk assessment. Science of The Total Environment, 2023, 868: 161739.

[16]  Ying Zhang, Ying Chen, Huijuan Chen, Yanfeng Zhang, Liping Yang, Wenjue Zhong, Lingyan Zhu*. Direct evidence of the important role of proteins in bioconcentration and biomagnification of PFASs in benthic organisms based on comparison with OPEs. Science of The Total Environment, 2023, 863: 161012.

[17]  Rongyan Yang, Yongxiu Ye, Ying Chen, Yi Yang, Liping Yang, Yiming Yao, Wenjue Zhong*, Lingyan Zhu*. First Insight into the Formation of In Vivo Transformation Products of 2-Ethylhexyl diphenyl phosphate in Zebrafish and Prediction of Their Potential Toxicities. Environmental Science & Technology, 2023, 57(1): 451–462.

[18]  Qiaoying Chen, Shujun Yi, Qingqing Ye, Yumin Zhu, Wenjue Zhong, and Lingyan Zhu*. Insights into the Dermal Absorption, Deposition, and Elimination of Poly- and Perfluoroalkyl Substances in Rats: The Importance of Skin Exposure. Environmental Science & Technology, 2022, 56(23): 16975–16984.

[19]  Yumin Zhu, Yibo Jia, Xiao Wang, Shujun Yi, Yuqing Li, Wenjue Zhong, and Lingyan Zhu*. Mechanisms Underlying the Impacts of Lipids on the Diverse Bioavailability of Per- and Polyfluoroalkyl Substances in Foods. Environmental Science & Technology, 2022, 56(6): 3613–3622.

[20]  Rongyan Yang , Xiao Wang , Jingwen Wang , Pengyu Chen , Qing Liu , Wenjue Zhong*, Lingyan Zhu*. Insights into the sex-dependent reproductive toxicity of 2-ethylhexyl diphenyl phosphate on zebrafish (Danio rerio). Environment International, 2022, 158: 106928.

[21]  Yao Li, Xiaoyong Yu, Xin Chen, Jun Yin, Wenjue Zhong, Lingyan Zhu*. Underlying mechanisms for the impacts of molecular structures and water chemistry on the enrichment of poly/perfluoroalkyl substances in aqueous aerosol. Science of the Total Environment, 2022, 803:150003.

[22]  Wenjue Zhong, Yannan Cui, Ruixuan Li, Rongyan Yang, Yao Li, Lingyan Zhu*. Distribution and sources of ordinary monomeric and emerging oligomeric organophosphorus flame retardants in Haihe Basin, China. Science of the Total Environment, 2021, 785:147274.

[23]  Xiaolei Wang, Qing Liu, Wenjue Zhong, Liping Yang, Jing Yang, Adrian Covaci, Lingyan Zhu*. Estimating renal and hepatic clearance rates of organophosphate esters in humans: Impacts of intrinsic metabolism and binding affinity with plasma proteins. Environment International, 2020, 134:105321.

[24]  Jing Yang#, Wenjue Zhong#, Pengyu Chen, Yinqing Zhang, Binbin Sun, Menglin Liu, Yumin Zhu, Lingyan Zhu*. Graphene oxide mitigates endocrine disruption effects of bisphenol A on zebrafish at an early development stage. Science of the Total Environment, 2019, 697:134158.

[25]  Pengyu Chen, Ruihan Wang, Jing Yang, Wenjue Zhong, Menglin Liu, Shujun Yi, Lingyan Zhu*. Stronger estrogenic and antiandrogenic effects on zebrafish larvae displayed by 6:2 polyfluoroalkyl phosphate diester than the 8:2 congener at environmentally relevant concentrations. Science of the Total Environment, 2019, 695, 10: 133907.

[26]  Menglin Liu, Shujun Yi, Pengyu Chen, Meng Chen, Wenjue Zhong, Jing Yang, Binbin Sun, Lingyan Zhu*. Thyroid endocrine disruption effects of perfluoroalkyl phosphinic acids on zebrafish at early development. Science of the Total Environment, 2019, 676: 290-297.

[27]  Guoqiang Shan#, Liping Yang#, Jinyu Zhao, Ning Liu, Haochen Cui, Wenjue Zhong, Lingyan Zhu . Identification and quantification of perfluorooctane sulfonamide isomers by liquid chromatography–tandem mass spectrometry. Journal of Chromatography A, 2019, 1594: 65-71.

[28]  Xiaolei Wang, Wenjue Zhong, Bowen Xiao, Qing Liu, Liping Yang, Adrian Covaci, Lingyan Zhu*. Bioavailability and biomagnification of organophosphate esters in the food web of Taihu Lake, China: Impacts of chemical properties and metabolism. Environment International, 2019, 125: 25-32.

[29]  Wenjue Zhong#, Liyuan Zhang#, Yannan Cui, Meng Chen, Lingyan Zhu*. Probing mechanisms for bioaccumulation of perfluoroalkyl acids in carp (Cyprinus carpio): Impacts of protein binding affinities and elimination pathways. Science of the Total Environment, 2019, 647: 992-999.

[30]  Pengyu Chen, Qiang Wang, Meng Chen, Jing Yang, Ruihan Wang, Wenjue Zhong*, Lingyan Zhu*, and Lihua Yang. Antagonistic Estrogenic Effects Displayed by Bisphenol AF and Perfluorooctanoic Acid on Zebrafish (Danio rerio) at an Early Developmental Stage. Environmental Science & Technology Letters, 2018, 5(11): 655–661.

[31]  Xiaolei Wang, Lingyan Zhu*, Wenjue Zhong, Liping Yang. Partition and source identification of organophosphate esters in the water and sediment of Taihu Lake, China. Journal of Hazardous Materials, 2018, 360: 43-50.

[32]  Wenjue Zhong, Yanfeng Zhang, Zihao Wu, Rongyan Yang, Xinyue Chen, Jing Yang, Lingyan Zhu*. Health risk assessment of heavy metals in freshwater fish in the central and eastern North China. Ecotoxicology and Environmental Safety, 2018,157: 343-349.

[33]  Wenjue Zhong, Donghong Wang*, Zijian Wang. Data on contents of fifty phenolic compounds in three rivers in Tianjin, China. Data in Brief, 2018, 18:124-130.

[34]  Wenjue Zhong, Donghong Wang*, Zijian Wang. Distribution and potential ecological risk of 50 phenolic compounds in three rivers in Tianjin, China. Environmental Pollution, 2018, 235:121-128.

[35]  Qiusen Huang, Qingwei Bu*, Wenjue Zhong, Kaichong Shi, Zhiguo Cao, Gang Yu. Derivation of aquatic predicted no-effect concentration (PNEC) for ibuprofen and sulfamethoxazole based on various toxicity endpoints and the associated risks. Chemosphere, 2018, 193:223-229.

[36]  Yanfeng Zhang, Yuwei Han, Jinxi Yang, Lingyan Zhu*, Wenjue Zhong*. Toxicities and risk assessment of heavy metals in sediments of Taihu Lake, China, based on sediment quality guidelines. Journal of Environmental Sciences, 2017, 62: 31-38.

[37]  Shuhong Fang, Shuyan Zhao, Yifeng Zhang, Wenjue Zhong, Lingyan Zhu*. Distribution of perfluoroalkyl substances (PFASs) with isomer analysis among the tissues of aquatic organisms in Taihu Lake, China. Environmental Pollution, 2014, 193: 224-232.

[38]  Wenjue Zhong, Donghong Wang*, Xiaowei Xu. Phenol removal efficiencies of sewage treatment processes and ecological risks associated with phenols in effluents. Journal of Hazardous Materials, 2012, 217–218 :286-292.

[39]  Jianfeng Tang, Shan Chen, Yiping Xu, Wenjue Zhong, Mei Ma, Zijian Wang*. Calibration and field performance of triolein embedded acetate membranes for passive sampling persistent organic pollutants in water. Environmental Pollution, 2012, 164:158-163.

[40]  Wenjue Zhong, Donghong Wang, Xiaowei Xu, Bingyi Wang, Qian Luo, Satyanarayanan Senthil Kumaran, Zijian Wang*. A gas chromatography/mass spectrometry method for the simultaneous analysis of 50 phenols in wastewater using deconvolution technology. Chinese Science Bulletin, 2011, 56:275–284

[41]  Wenjue Zhong, Donghong Wang, Xiaowei Xu, Qian Luo, Bingyi Wang, Xiaoquan Shan, Zijian Wang*. Screening level ecological risk assessment for phenols in surface water of the Taihu Lake. Chemosphere, 2010, 80( 9): 998-1005.

[42]  钟文珏，张瑜，祝凌燕*. 沉积物中芘对淡水底栖动物的急慢性毒性效应. 中国环境科学, 2017,37(7):2765-2772

[43]  韩雨薇，张彦峰，陈萌，钟文珏，祝凌燕*. 沉积物中重金属 Pb 和 Cd 对河蚬的毒性效应研究.生态毒理学报,2015，10( 4) : 129-137.

[44]  钟文珏，张瑜，韩雨薇，祝凌燕*. 沉积物中五氯酚对底栖生物的急慢性毒性效应.生态毒理学报, 2015，10(1): 297-304.

[45]  刘丽，钟文珏，祝凌燕*. 沉积物中六氯苯对摇蚊幼虫的慢性毒性效应.生态毒理学报, 2014，9( 2) : 261-267.

[46]  赵淑艳，马新新，钟文珏，方淑红，祝凌燕*. 蚯蚓对土壤中8：2与10：2氟调醇的生物富集与转化. 中国科学:化学，2014，44(11):1823-1830

[47]  钟文珏，曾毅，祝凌燕*. 水体沉积物质量基准研究现状. 生态毒理学报, 2013，8(3) : 285-294.

[48]  魏明翠, 钟文珏, 赵丽霞, 祝凌燕*. 南方某氟化学工业园周围环境中全氟化合物的分布研究. 环境科学学报, 2013, 33(7):1989-1995

[49]  张婷，钟文珏，曾毅，祝凌燕*. 应用生物效应数据库法建立淡水水体沉积物重金属质量基准.应用生态学报, 2012，23( 9) : 2587-2594.

[50]  曾毅，钟文珏，祝凌燕*，刘楠楠. 太湖地区全沉积物毒性识别评估研究.中国科学:化学, 2012, 42(8):1234-1241

[51]  钟文珏, 常春, 曾毅, 祝凌燕*. 非离子有机物淡水沉积物质量基准推导方法—以林丹为例.生态毒理学报, 2011, 6(5): 5,476-484.

[52]  钟文珏，王东红，徐小卫，原盛广，王子健*. 再生水中优先控制有毒污染物的筛查方法. 中国环境科学，2011,31(2):332-339

[53]  徐小卫, 王东红, 钟文珏, 王炳一, 刘淑琴. 2种再生水深度处理工艺对有毒有机污染物去除效果的评价研究, 环境工程学报, 2011，5(5): 971-976

2022 年南开大学教学成果奖校级一等奖

2019 年中国科学技术协会第四届优秀科技论文遴选计划入选论文

《中国环境科学》2017年度十佳论文

2014 年度环境保护科技奖一等奖项目
天津市三年引进千名高层次人才计划获得者