陈则友

发布者:envadmin发布时间:2019-06-12浏览次数:19345


姓名:陈则友
职称:副教授、博导

研究领域:环境微生物学、微生物生态学、环境化学

研究兴趣:

1. 抗生素的环境行为过程和生态健康危害;

2. 环境中抗生素抗性基因和抗性细菌的来源分布、传播扩散和健康风险。

邮箱: zeyou@nankai.edu.cn

教育背景

2013.10—2016.6,美国密西根州立大学,联合培养博士
2010.9—2016.6,南京农业大学,硕博连读

科研教学经历

2019.02至今,南开大学,环境科学与工程学院,副教授

2017.12-2018.12,南京大学,环境学院,助理研究员

2016.6-2017.11,美国密西根州立大学,土壤、植物和微生物系,博士后

2020年至今,讲授本科生课程《简明分子生物学》。

科研项目

1. 国家自然科学基金面上项目(42277386, 消毒剂协同选择公共设施表面细菌产生抗生素抗性的机制和风险,53万,2023,1-2026.12(主持)。

2. 国家重点研发计划青年科学家项目(2022YFC3700216),土壤及地下水中高风险病原体污染及防控,60万,2023.1-2025.12(课题负责人)。

3. 国家重点研发计划 “场地土壤污染成因与治理技术”2020年度重点专项(2020YFC1806900),场地抗生素及抗性基因环境行为与健康风险,100万,2020.11-2024.10(子课题负责人)。

4. 国家自然科学基金面上项目(41977367),耐药性人类条件致病菌及其携带的耐药基因在土壤-植物系统中的传输规律、扩散机制及健康风险研究,61万,2020.1-2023.12(主持)。

5. 国家自然科学基金青年项目(41807483),利用全细胞微生物传感器研究四环素的典型环境行为对细菌抗性基因表达的影响及机理,25万,2019.1-2021.12(主持)。

6. 江苏省自然科学基金青年项目(BK20180347),抗生素抗性基因在动物粪便-好氧堆肥-农田施用全过程中的迁移和归趋研究,20万,2018.7-2021.6(主持)。

7. 南京大学中央高校基本科研业务费专项资金资助(021114380099)。利用全细胞微生物传感器研究四环素的典型环境行为对细菌抗性基因表达的影响及机理,10万,2018.1-2018.12(主持)。


学术与社会任职

1.   1. Journal of Hazardous Materials Advances 青年编委

2.   2.  Bulletin of Environmental Contamination and Toxicology (BECT) 青年编委

3.   3.  Frontiers in Microbiology 专刊客座编辑

4.   4. “Environmental Microbiology, Environmental Science & Technology, Water Research”等杂志审稿人


学术论著

10篇代表性著作#co-first author,* corresponding author

1. Zeyou Chen, Wei Zhang, Anping Peng, Yike Shen, Xin Jin, Robert D. Stedtfeld, Stephen A. Boyd, Brian J. Teppen, James M. Tiedje, Cheng Gu, Dongqiang Zhu, Yi Luo, Hui Li*.Bacterial Community Assembly and Antibiotic Resistance Genes in Soils Exposed to Antibiotics at Environmentally Relevant Concentrations. Environmental Microbiology. 2023. DOI: 10.1111/1462-2920.16371.

2. Lichun Yin, Xiaolong Wang, Han Xu, Bo Yin, Xingshuo Wang, Yulin Zhang, Xinyao Li, Yi Luo, Zeyou Chen*,Unrecognized Risk of Perfluorooctane Sulfonate in Promoting Conjugative Transfers of Bacterial Antibiotic Resistance Genes. Applied and Environmental Microbiology. 2023;89(9):e0053323.

3. Han Xu, Zeyou Chen *, Ruiyang Huang, Yuxiao Cui, Qiang Li, Yanhui Zhao, Xiaolong Wang, Daqing Mao, Yi Luo *.Antibiotic Resistance Genes-carrying Plasmid Spreads into the Plant Endophytic Bacteria by Soil Bacteria as Carriers. Environmental Science & Technology. 2021, 55(15)10462-10470.

4. Xiaolong Wang(#), Zeyou Chen (#), Quanhua Mu, Xinyan Wu, Jingjing Zhang, Daqing Mao, Yi Luo, Pedro J. J. Alvarez, Ionic liquid Enriches the Antibiotic Resistome, Especially Efflux Pump Genes, Before Significantly Affecting Microbial Community Structure.Environmental Science & Technology,2020, 54, 7, 4305-4315

5. Zeyou Chen, Wei Zhang, Wang Gang, Yingjie Zhang, Yanzheng Gao, Stephen A. Boyd, Brian J. Teppen, James M. Tiedje, Dongqiang Zhu, and Hui Li. Bioavailability of Soil-sorbed Tetracycline to Escherichia coli under Unsaturated Conditions. Environmental Science & Technology. 2017:51:6165-6173.

6. Zeyou Chen, Yingjie Zhang, Yanzheng Gao, Stephen A. Boyd, Dongqiang Zhu, and Hui Li. Influence of Dissolved Organic Matter on Tetracycline Bioavailability to an Antibiotic-Resistant Bacterium. Environmental Science & Technology. 2015:49: 10903−10910.

7. Anping Peng, Chao Wang, Zhanhua Zhang, Xin Jin, Cheng Gu, and Zeyou Chen, * Tetracycline photolysis revisited: overlooked day-night succession of the parent and metabolites in natural surface waters and associated ecotoxicity. Water Research. 2022, 225:119197.

8. Jie Hou(#), Zeyou Chen (#), Ju Gao, Yonglei Xie, Linyun Li, Songyan Qin, Qing Wang, Daqing Mao, Yi Luo, Simultaneous removal of antibiotics and antibiotic resistance genes from pharmaceutical wastewater using the combinations of up-flow anaerobic sludge bed, anoxic-oxic tank, and advanced oxidation technologies. Water Research, 2019:159:511-520.

9. Lei, Liusheng, Nan Chen, Zeyou Chen*, Yirong Zhao, Huai Lin, Xi Li, Wenjin Hu, Hanhui Zhang, Jingliang Shi, and Yi Luo*. Dissemination of antibiotic resistance genes from aboveground sources to groundwater in livestock farms.Water Research.2024;256: 121584.

10. Chen, Zeyou, Yulin Zhang, Daqing Mao, Xiaolong Wang, and Yi Luo. NaClO Co-selects Antibiotic and Disinfectant Resistance in Klebsiella pneumonia: Implications for the Potential Risk of Extensive Disinfectant Use during COVID-19 Pandemic. Journal of Hazardous Materials (2024): 134102.